As a side note, there been ocations where the antivirus puts the pulsesd.exe and/or the contents of the “C:\Program Files\Pulse for TM1\webapps\ROOT\WEB-INF” folder in the quarantine. Also ensure that the Pulse For TM1 folder and subfolders are skipped by the antivirus.
We had the very same issue the last couple of weeks. We found that a recent Microsoft security patch caused the issues. Microsoft has now issued a fix for the failing patches:
Below are the patches planned to be installed based on the OS type
We have recently solved and issue where the port 8099 was unavailable in the Server, regardless that it was configured in the outbound/inbound rules in the firewall. Connecting to pulse through the SSL port (8093) demonstrated the issue, In this case there was no more option rather to reboot the box as it was Windows issue.